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Complete genomic characterization of cell culture adapted human G12P[6] rotaviruses isolated from South Korea
- Van Thai Than;
- Van Phan Le;
- Lim, Inseok;
- Kim, Wonyong
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11초록
Two unusual human rotavirus G12 strains, CAU195 and CAU214, were isolated from female pediatric diarrhea patients under 12 months of age in 2006 using a cell culture system and their full genome sequences were analyzed. The 11 gene segments of both Korean G12 strains were classified as G12-P[6]-R1-C1-M1-I1-A1-N1-T1-E1-H1 genotypes. Notably, the Korean strains were of the same genotypes as previously reported strains isolated from Bangladesh in 2003 (Dhaka12-03), from the United States in 2005-2006 (US6597), and from Germany in 2008 (GER126-08 and GER172-08), suggesting that closely related G12P[6] strains are persistent and widespread.
키워드
G12; Korean rotavirus; Phylogenetic analysis; GROUP-A ROTAVIRUS; POLYMERASE CHAIN-REACTION; SEROTYPE G12 ROTAVIRUSES; MOLECULAR CHARACTERIZATION; UNITED-STATES; STRAINS; CHILDREN; DIARRHEA; EMERGENCE; GENOTYPES
- 제목
- Complete genomic characterization of cell culture adapted human G12P[6] rotaviruses isolated from South Korea
- 저자
- Van Thai Than; Van Phan Le; Lim, Inseok; Kim, Wonyong
- 발행일
- 2011-06
- 유형
- Article
- 저널명
- Virus Genes
- 권
- 42
- 호
- 3
- 페이지
- 317 ~ 322