Cost-Effective Culture Medium for Cell-Based Future Foods

  • Park, Sohyeon; 
  • Lee, Hyun; 
  • Jung, Sungwon; 
  • Choi, Bumgyu; 
  • Lee, Milae; 
  • ... Lee, Sangmin; 
  • 외 3명
Citations

WEB OF SCIENCE

12
Citations

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12

초록

Cell-based protein sources are considered promising future food materials due to their nutritional potential and sustainability. However, the process of massive cell proliferation, which involves an expensive culture medium and is time-consuming, slows the development of cell-based future foods. Herein, we report on the development of cost-effective culture media prepared from egg whites, microalgae, and silk extracts. The developed culture media showed cell proliferation efficiency similar to that of the conventional medium group while maintaining the bovine myoblasts in an undifferentiated state. Furthermore, an improved degree of myogenic differentiation was observed in myoblasts proliferating using the developed culture medium. We selected the optimal cell culture medium for food production by deriving the cost-effectiveness of each culture medium for cell growth. This research provides fundamental insights into building sustainable food systems and cellular agriculture.

키워드

Bovine myoblast; mass proliferation; pluripotency; culture medium; cultured meat; future food; cost-efficiency; C-PHYCOCYANIN; DIFFERENTIATION; INFLAMMATION; STABILITY
제목
Cost-Effective Culture Medium for Cell-Based Future Foods
저자
Park, Sohyeon; Lee, Hyun; Jung, Sungwon; Choi, Bumgyu; Lee, Milae; Jung, Se Yong; Lee, Seung Tae; Lee, Sangmin; Hong, Jinkee
DOI
10.1021/acssuschemeng.3c02972
발행일
2023-09
유형
Article
저널명
ACS Sustainable Chemistry & Engineering
권
11
호
38
페이지
13868 ~ 13876