Electro-triggering and electrochemical monitoring of dopamine exocytosis from a single cell by using ultrathin electrodes based on Au nanowires

Kang, Mijeong; Yoo, Seung Min; Gwak, Raekeun; Eom, Gayoung; Kim, Jihwan; Lee, Sang Yup; Kim, Bongsoo

doi:10.1039/c5nr06021d

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Electro-triggering and electrochemical monitoring of dopamine exocytosis from a single cell by using ultrathin electrodes based on Au nanowires

Kang, Mijeong;
Yoo, Seung Min;
Gwak, Raekeun;
Eom, Gayoung;
Kim, Jihwan;
외 2명

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13

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14

초록

A sophisticated set of an Au nanowire (NW) stimulator-Au NW detector system is developed for electrical cell stimulation and electrochemical analysis of subsequent exocytosis with very high spatial resolution. Dopamine release from a rat pheochromocytoma cell is more stimulated by a more negative voltage pulse. This system could help to improve the therapeutic efficacy of electrotherapies by providing valuable information on their healing mechanism.

키워드

DEEP BRAIN-STIMULATION; VESICULAR EXOCYTOSIS; PC12 CELLS; SYNAPSES; RELEASE; ARRAYS

제목: Electro-triggering and electrochemical monitoring of dopamine exocytosis from a single cell by using ultrathin electrodes based on Au nanowires

저자: Kang, Mijeong; Yoo, Seung Min; Gwak, Raekeun; Eom, Gayoung; Kim, Jihwan; Lee, Sang Yup; Kim, Bongsoo

DOI: 10.1039/c5nr06021d

발행일: 2016-01

유형: Article

저널명: Nanoscale

권: 8

호: 1

페이지: 214 ~ 218

언어: ENG

출판사: ROYAL SOC CHEMISTRY

발행국가: 영국

분량: 5 페이지

ISSN: E 2040-3372
P 2040-3364